Along with my fellow Sophos bloggers, I'm currently attending VB2010, this year's Virus Bulletin conference, in sunny (honestly!) Vancouver, BC.
My first trip to Vancouver was in 1999, the first time VB took place in the Pacific North West. (It was raining.)
Script-based malware was a big deal back then – Microsoft Office viruses were still an enormous problem, despite already being in decline. And malware was almost always written as a crime in its own right, rather than as a vehicle to commit further cybercrimes, as it is today.